Indy is a classic midwestern city, sprawling and laid out on an unrelenting grid pattern with a few diagonal streets for variety. US40, the current alignment of the old National Road cuts through from east to west.
If you look hard enough, you can find neighborhoods form every period from the mid-1800’s to the present. Historic districts here have the typical midwestern sensibility (“people still have to live there so let’s not turn it into Disneyland”).